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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

但3D版吉祥猴的形象却未能避开炮击,挑剔的网友纷纷吐槽:“这让我想起红绿灯!”;“水墨画的精髓全然不见”;“耳朵下面的两个球是什么呀,太抢镜了……”;“已被它丑哭。”
decision

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

拍卖行称这次拍卖会还将拍卖两颗超过100克拉的钻石,吸引了30多个国家的买家。
如果你已经为人父母,我能够理解,这是不太可能的。你会将孩子放在更重要的位置。但是,如果你没有在课堂上展示自己,那么你也就没有做到我们在第一点里讨论的内容。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

从事房地产业的中国女富豪最多,占23%,金融投资业占18%,制造业占14%。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

国务院总理李克强在上周五由人力资源和社会保障部组织的一次会议上表示,要优先促进就业。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

n. 信用,荣誉,贷款,学分,赞扬,赊欠,贷方
如果说2017年是政策制定者们开始担心“无保障无产阶级”(precariat)人数增长的一年,那么2018年将是他们尝试为此做些什么的一年。
但许多人预测将会出现经济崩盘,他们认为,旷日持久的欧元区危机加上房地产泡沫,将使相当大一部分中国工业失去盈利能力。这将暴露出各种隐藏的金融脆弱性,推动形成一场螺旋式下降。其他人认为,北京方面有充足的资源可以避免一场危机,不过他们指出,由于中国的增长模式依赖于基建和土地出售,且汇率和利率受到僵硬控制,它也许并没有所有必要工具。
ec出,centri中心一出中心一古怪的;离心的

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 业主们 这些隐形收益你们知道吗
Perspective

Trends and targets in antiviral phototherapy

Right now, she's focusing on her modeling career, but also hopes to branch out into acting.
Saif held the highest position among the five ranked Chinese schools, just ahead of Guanghua School of Management and Tsinghua University School of Economics and Management, 17th and 18th respectively.
I'm only a child yet I know we are all part of a family, five billion strong, in fact, 30 million species strong and we all share the same air, water and soil -- borders and governments will never change that. 我只是一个小孩,但我知道我们都是一个大家庭的成员,超过60亿人的大家庭,以及超过三千万物种的大家庭,政府和国界永远都无法改变这个事实。
Human bodies are frail, easily damaged packages full of parts that can never fully come back once lost. Luckily, researchers worldwide are working on replacing every bit of the body to make us all cyborgs.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

You are so engaged in thinking of him that you don't notice that there is no No.12.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Siddeeq现在已经是一位退休教师居住在中西部城市Indianapolis,他表示当大学联系到他的时候他震惊了。
In the three years after the death of Steve Jobs, Mr Cook, 54, has held his nerve through attacks from activist investors and a loss of faith among some that Apple could succeed without its late founder. This year has seen Apple’s chief step out of the shadows of his predecessor and imprint the company with his own set of values and priorities: bringing in fresh blood, changing how it manages its cash pile, opening Apple up to greater collaboration and focusing more on social issues.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

['pr?p?ti]
中国国家旅游局周五发出通知,确认了最近几个月中国游客因所持旅游文件不完整而被拒进入韩国济州岛的报道。该机构提醒中国公民“慎重选择旅游目的地”。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Quite a few students were disillusioned by UK visa regulations. “A lot of people saw the programme as a gateway to employment in Europe,” says one. “If this was the objective, then a lot of them would have gone away unfulfilled.”
办公室总有一两个让人让大多数人都无法容忍的人,但是如果你不喜欢大多数的同事,那么你的工作就会变得不愉快因为你不得不整天和他们在一起工作。如果你再也不能容忍他们,试试找一个你能够和里面的职员和平相处的公司了。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

我可能会说:“我解雇你是因为你工作不达标。”实际上,我并不会说是因为你实在让人受不了,每次和人沟通都会得罪人。
中国投资10亿美金用以将进一步打造C9大学(中国最好的9所大学)。 经费将会主要用来吸引顶级的教职人员,建造世界一流的教学设施,和招募一流的声源。中国将会国际智力、教育和技能的人才大战中逐鹿。
The exchanges revealed there is little major difference between the two in term of their approach to security and foreign affairs. On Iran both vowed it will not be allowed to have nuclear weapons. Rommey said he would introduce more stringent sanctions; Obama said they were already as stringent as they could possibly be.
作为回应,维尔德斯把吕特归为骗子,指责后者未能遵守在2012年选举期间做出的不支持纾困希腊的承诺。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

克普克表示,就1994-95年墨西哥汇率危机而言,三个因素都起了作用,当时美联储开始以25、50甚至75个基点(1994年11月)的加息幅度进入紧缩周期。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 民宿期待一场品质革命
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

出演《美国队长3:英雄决裂》的斯嘉丽-约翰逊排名第三,收入为2500万美元,比去年下降了近30%。
Big-spending US firms are forcing their UK counterparts to increase salaries right the way from newly qualifieds to the top rainmakers — though that did not stop David Higgins, private equity star at Freshfields, from decamping to Kirkland & Ellis just before Christmas. Boutique specialists are luring clients away by offering faster, more focused services.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

斯特罗恩表示,他认为IP-BOX运用了和FBI没有经过苹果公司的帮助而破解塞义德·法鲁克iPhone 5c相同的技术。现在FBI已经开始向其他执法部门提供帮助解锁iPhone,iPad或者iPod Touch的方法。苹果方面正在积极寻找FBI是如何破解iPhone的,并将推出软件更新来关闭这些漏洞。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

suc下面,cumb躺-躺下去-屈从

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

WHAT: A riverfront contemporary with three bedrooms and three and a half bathrooms
当时的杜兰特身高6尺9寸,体重只有185磅,我很惊讶在高中赛打到一半时他没有被撞坏。幸运的是,杜兰特不靠在大前锋位置上力量抗衡赚钱,他主要依赖他拿手的急停跳投。
除了众多受过教育的劳动力可供选择,企业也被亚利桑那州的亲商监管环境所吸引,在莫卡特斯中心(Mercatus Center)发布的美国50个州商业自由度排行榜上,亚利桑那州排名第13位。这项研究援引亚利桑那州的劳动权利法、责任法和土地征用权改革作为有利条件。
目前还不清楚绑架者的身份以及他们的目的。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Polls indicate that the Dutch election will be extremely tight. Mr Rutte’s centre-right VVD sits atop most polls, just 3 percentage points ahead of the PVV. Most polls show a large percentage of voters remain undecided.
Vietnamese press claim chicken, sturgeon, fruit and vegetables from China have been undercutting local market prices. While illegal out-of-date produce is creating a black market in China.
中国首先要把自己的事情办好,但关起门来也办不好自己的事情。所以我们的开放大门会越开越大。
有迹象显示,人们对公务员的热情可能正在消减,招聘网在三月底发布的一份报告称,仅仅两个月,已有1万多名公共单位职员通过该网站提交了简历,其中包括公务员和公共机构工作人员。报告还表示,去年同一时期,提交简历的人数比今年高34%。
The 62 universities account for 12.4% of the list. The only country with a larger number of universities listed is the US, which accounts for 27.8%.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

purchase
For years, slow emissions declines in the West have been swamped by rising emissions in the East, and the trend continued in 2013. China's emissions grew 4.2 percent and India's 5.1 percent. Both countries have been constructing coal-burning power plants at a breakneck pace.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

本次问卷调查的主要对象为中国高校2017年应届毕业生,包括大专、本科、硕士及博士等,智联招聘最终收回有效样本93420份。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

The economy will grow 3% for the first time in 10 years

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

“我们内地的执法太不严了,一帮导演到了新加坡不敢抽烟,可是到了珠海,在有警告的情况下依然抽!所以我们的执法一定要严!”
Investors have noticed Honda’s troubles. The automaker was one of the very few worldwide to avoid deep losses during the global financial crisis. Still, its common shares are down 17.2% over the past year, while the Nikkei 225 Index is up 7.4% and Toyota Motor shares are up 19.5%.
明年,寻找新楼盘的买家将会有更多的选择。根据科克伦阳光营销集团(Corcoran Sunshine Marketing Group)提供的数据,明年(2015年——译注)曼哈顿、布鲁克林和皇后区长岛市(Long Island City)新上市的共管公寓预计将增加一倍以上,从2014年的3444套增加到8366套。
在这个力求避免任何歧视的态度的年代,年轻一代开始不满邦德的大男子主义态度和不健康的生活方式,因此赫洛维兹引入了一系列会指出邦德错误的新人物。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Iron Man 3 is the highest-grossing movie of 2013 so far with $1.2 billion. But that’s not enough to put its star, Robert Downey Jr., on top of our list of the top-grossing actors. Dwayne “The Rock” Johnson beat him this year by working more.
CONTACT: Debbie McNally, Lakes Sotheby’s International Realty, (612) 388-1790; debbiemcnally.com
1.你一夜之间成了领英平台的香饽饽。
《江城警事》(Battle Creek),CBS,3月1日播出。重磅剧就是会带来这样的改变。文斯·吉利根在十几年前就为这部亦敌亦友的警探搭档剧写好了试播集剧本,当时他还不是《绝命毒师》与《风骚律师》的主创。如今它终于被CBS拍成13集连续剧了。《法律与秩序:特殊受害者》(Law & Order: SVU)和《我为喜剧狂》(30 Rock)的主演在剧中饰演一个当地警探,《拉斯维加斯》(Las Vegas)主演乔希·杜哈明(Josh Duhamel)饰演一个老练的联邦调查局探员,两人在密西根州巴托溪的塞里尔城共事,相处得很不自在。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 北京市住建部门专项检查通州中介
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Nearly half of the Kings' roster should have been traded following the Cousins teardown move and yet none were. Nice. Bring on Buddy Mania. Plenty of good seats still available.
For as long as the show has been running — ever since its debut in 2007 — we have been, it seems, suffering from what Hadley Freeman in The Guardian newspaper dubbed “madmenalaria.”

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

一些最近发表的科学论文说,高空急流中这种持续较长的怪现象,由于全球变暖正在导致北极地区海洋中的冰迅速融化而变得更可能发生,但许多主要的科学家还没有被这种观点说服。
n. 模子,模型,类型,模式,雏型,真菌,软土
Andersl?v, Sweden was plagued by residents with green hair. Johan Pettersson discovered that there was too much copper in their water.
中国信息通信研究院的报告称,2016年国产手机出货量达4.98亿部,占国内手机总出货量的88.9%。
These are the official James Bond theme songs, ranked from worst to best, with two honorable mentions because they may or may not count, but were just that good, dang it.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

据金融数据提供商Wind Information有限公司,列出了去年在整个A股市场共实现净利润2.47万亿元的各家公司。在这些上榜公司中,其中有2000家拟进行现金分红,总额近7000亿元。
Mr Erdogan, who has also benefited domestically from the row with Mr Rutte, has sought to broaden his diplomatic dispute to take on all of the EU, particularly Germany, which has had similar run-ins with Ankara over campaigning in Germany’s large Turkish community.
However, the economists polled expect slightly higher growth rates and substantially higher inflation over 2016.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

check
创始人的心态将为公司定下基调。消极、懒惰和理所应当的心态,不仅浪费时间和金钱,还会损害你的信誉。成功很大程度上取决于能否在犯错后从容地接受批评。直面挑战可以让一位普通的公司老板变成真正的领导者。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Sweden, one of the most generous countries in terms of contributing funds to humanitarian aid, ranks No. 6 overall. The country is No. 2 in Citizenship and No. 1 in Best Countries for Green Living.
它会自然生长成模子的形状。
The 2016 ranking features a record 90 programmes, up from 70 in 2014.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

9. 安布罗斯·阿钦摩西尔(Ambrose Akinmusire),《想像中的救世主更容易描绘》(the imagined savior is far easier to paint),Blue Note。小号手安布罗斯·阿钦摩西尔为自己在Blue Note公司发行的第二张专辑注入了类型不固定,富于探索精神的今日之声,有许多歌手和一支弦乐四重奏组合参与。和这张专辑刚发行的时候相比,如今的他有了更多评论社会的迫切与讥讽时局的精神。
At New Year and always, may peace and love fill your heart, beauty fill your world, and contentment and joy fill your days.
[dr?ft]

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 国企一季度税后净利润增18.6%
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

年龄对詹姆斯仍不是问题

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 2015年1-9月中国涂料产量1237.97万吨
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Welcome as they were, surging sales weren't the biggest news of the year. Detroit celebrated when General Motors (GM, Fortune 500) made Mary Barra the auto industry's first female CEO, then held its breath while Ford (F, Fortune 500) CEO Alan Mulally dithered over a move to Seattle and Microsoft. The old Big Three, complaining about straining available production capacity, made plans to expand and hire. Tesla(TSLA) fired up electric car sales and refused to play by industry's rules, while Google(GOOG, Fortune 500) pioneered a car that drives itself.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

deprivation
Domain name registrar GoDaddy, which is based in Scottsdale, Ariz., broke ground in May on its new Global Technology Center in Tempe. GoDaddy already employs 2, 600 people in the Greater Phoenix area and the new facility is expected to add 300 more. Other companies expanding in Arizona include Asurion, a leader in technology protection services. They opened a new technical support center in Phoenix and want to fill 500 jobs by the end of the year. Energy provider Direct Energy opened a new call center in Tempe this year and is looking to fill as many as 300 openings.

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

“我不知道发生了什么”洛瑞说。“我只知道我被吹罚了一次进攻犯规,就这么发生了。这就是NBA,这就是我想说的。”
尽管榜单上以法国和英国学校居多,占全部上榜学校的44%,但今年的排行榜比以往任何时候都更多元化,上榜学校来自25个国家。
It is not yet known who will look after Choupette after Lagerfeld's death.
Although the original book got 7.9 out of 10 on Douban, the TV version only got 5 for its poor adaptation.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

“Through the second half of the 20th century we had this big dispersion of trade and economic activity around the world. All this specialisation meant exports rose faster than GDP,” Mr Williams says.
这个所谓的“百万富翁的游乐场”现已向所有人敞开怀抱。经济型的酒店、家庭旅馆以及带有自助厨房的公寓,都使得塞舌尔之行不再价格高昂。塞舌尔由100多个散布在印度洋上的岛屿组成,这里有多种多样的娱乐活动供您选择,诸如沙滩浴、钓鱼、潜水、航海和乘船游览。塞舌尔群岛一年四季的热带气候可谓得天独厚,所以你随时都可以开始你的塞舌尔之行。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Ninety percent of the students believe their universities' guidance on entrepreneurship would help their future businesses. In addition, they professed appreciation for policies intended to encourage entrepreneurship.
9. 《奎迪》(Creed),导演:瑞恩·库格勒(Ryan Coogler)。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

据中央电视台报道,她的妈妈在1月30日才发现了此事。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

热门的新兴市场基准债券和股票的价格已经下降,同时根据代表全球大型金融公司的组织——国际金融研究所(Institute for International Finance)的数据,来自海外投资者的净流入已经从2014年的2850亿美元降至今年的660亿美元。
目前已经被泄露的照片多达10个G。据《北京日报》12月1日报道,著名在线P2P借贷平台"借贷宝"也和此次事件有关。
9. The Chinese militarywill demand and receive vastly expanded investments in the form of advancedaircraft and ships.
8. Across the world,China will continue to flex its might with acquisitions and transactions. Theone million Chinese in Africa will continue their efforts to lock up naturalresources.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

可以想象,2016年油价将从当前不到40美元的水平上反弹。沙特或许会尝试减产,伊拉克可能会爆发更多冲突,恐怖主义分子可能会攻击一些重要目标,比如沙特拉斯坦努拉和阿巴奇克的石油终端。一切皆有可能,有些事情发生的可能性更大一些。但问题在于,油价反弹的幅度将有多大?
['k?mf?t]

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

首次发现直接由禽类传染人类的流感病毒,此病毒的传染与接触家禽市场有关。香港有六人死亡。这种病毒之所以不同,是因为它并没有通过传染猪,使猪成为中间宿主,而是直接由鸡传染给人类。另外,年轻人中感染最严重的病症有些与1918年“西班牙流感”病毒相似。
['limitid]
去年12月份达成的预算协议很难称得上是华盛顿激辩多年所希望看到的、能够提振信心的协议,但至少它为华盛顿不断上演的政治博弈按下了“暂停”键。在过去三年中,华盛顿每年都会上演的这种博弈对经济的复苏构成了威胁。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

The ranking is based on data collected from two surveys: one of the participating business schools and the other of alumni who graduated three years ago — the class of 2013.
"Premier Wen Jiabao's speech had a big focus on economic and social development. It's clear the government is working very hard to bring about the goal of building a prosperous society."
encouragement

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

贝拉是该榜单上最年轻的模特,她上个月刚满21岁。
在即将结束的2014年,标普500指数再次实现亮眼增长,而那些本欲跑赢该指数的基金经理们,表现则没那么出色。Lipper公司称,截止11月底,85%的活跃股票型共同基金经理业绩低于标普500指数。而在正常的年份里,跑赢该指数的基金经理比例是今年的两倍,也就是说,通常只有约三分之二的基金表现不如标普500指数。Lipper公司称,这是30年来活跃基金经理相对大盘表现最差的一年。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

从10年和20年的时间跨度来看,地域和资产类别的多元化已经证明对投资回报和风险管理有益。不幸的是,在12个月内,不一定能看到此种战略的好处。在如今这个140字微博消息和2分钟短视频盛行的时代,投资者不能以长期的表现来判断其投资组合的成败,又有何奇怪?
《帕丁顿熊2》
The prince said authorities could recover as much as $100 billion in settlements.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

巴韦贾同意这一结论,他指出,韩国和另一个大宗商品净进口国印度,都是成品油的出口国。以美元计算,这些成品油的价值今年应会上升。
US billionaires hold 540 spots on the list, more than any other country in the world. In second is China with 251 and German with 120.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Continued experimentation with wearables is important, but the near-term requires a conversation “about whether current wearables, driven by a combination of organic efforts and corporate tech efforts, are really adhering to customer needs and wants or if companies need to explore a different set of partnerships to push wearables beyond early adopters and into the mainstream,” Gilbert says.
时间:2009-09-16 编辑:vicki
Trade flows brought China’s balance of trade to $40.82bn, roughly $7.2bn below expectations and down about $3.6bn from November’s revised level of $44.23bn (previously $44.61bn). That balance came to Rmb275.4bn in local-currency terms.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

恭贺新年。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

统计数据显示,在2009年之前,全球研发支出以每年约7%的速度增长,但在2014年放缓了4%。
公司:网络投票公司Everyone Counts

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

单词unique 联想记忆:
"Perhaps it is no big deal whether or not you are in the group discussion, but if you were absent, 670,000 people would be absent, if you were silent, 670,000 people would be silent."

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

世界知识产权组织总干事弗朗西斯.高锐在记者会上表示“中国的表现必须予以强调,他们的排名排到了第25位,与那些多年来一直位居全球创新指数前列的高收入国家比肩而立。”
This is the sixth edition of the QS World University Rankings by Subject, featuring a record-breaking 42 disciplines, making it the largest-ever ranking of the kind. The expert opinion of the world's top 76,798 academics and 44,426 employers informed the results, alongside the analysis of 28.5 million research papers and over 113 million citations sourced from the Scopus/Elsevier bibliometric database, said QS.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

对罗西(Pete Rossi)来说,这一年里有多少周工作超过50小时用一只手就能数得过来。而余下时间里,美国国防部精算师这个工作让他能以极小的压力过着高品质的生活。
在交易截止日到来前,看清楚他们会往哪个方向走这件事将会十分有趣。他们有很多靠得住的球员团结在布鲁克-洛佩兹身边。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

About 200 million migrants, half of whom are women, sent $445 billion to their families in Asia, Latin America and Africa in 2016, the International Fund for Agricultural Development (IFAD) said last Wednesday.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 根治“房闹”须坚持“房住不炒”
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

我们不希望通过贬值来增加出口,这不利于企业转型升级。
One year after new measures were implemented, Shanghai saw a year-on-year increase of six times the number of permanent residence applications from foreigners and their families.
In 2016, fear and anger became dominant political emotions in the UK and the US — two of the most important, stable and enduring democracies.
东京大学(全球排名22名)和京都大学(35名)仍然是亚洲最顶尖的两所高校。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 吉林德惠火殇:建材易燃不达标
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Brain death is a bit of an inconvenience if you're a fan of living, and if you're looking to replace yours with a spare, you're out of luck. Sure, maybe we'll one day be able to plant brains into skulls, but the brain's not just another organ. It contains all your thoughts and memories. They can plop a new brain in your head, but you'll still be gone, so the idea of making artificial brains may seem absurd.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

尽管随着租赁成本的上升和失业率的下降,薪酬最终会会上升;商人们将会在招聘劳动力上付出更多的成本而且还有可能由于缺乏员工以增加产量而导致销售量下降的风险。
最佳豪华汽车品牌:保时捷
The clip, taken on a mobile phone, starts with the crowd singing the Frankie Valli lyrics: You're just too good to be true, can't take my eyes off of you'.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Mr Cook has added three women to what was previously a white-male-dominated executive team and changed Apple’s board charter to commit to seeking out candidates from minorities when appointing directors.
停战日在1938年成为美国的正式节日,但在1954年改称退伍军人节。当时是第二次世界大战和朝鲜战争结束不久。退伍军人节跟每年五月最后一个星期一的阵亡将士纪念日不同。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The list also has some movies that earned awards at the 67th Berlin International Film Festival in February, such as the best movie winner On Body and Soul and best director winner The Other Side of Hope, by Aki Kaurismaki of Finland.
In early November the government further tightened controls over outbound investment by requiring regulatory approval for some foreign acquisitions conducted through an offshore entity.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

我以前曾有过一款安卓手机(尽管2009年以来我一直用的是MacBook笔记本电脑,这种搭配挺诡异的,我知道)。自从今年夏天换了iPhone以后,我马上意识到了iPhone“提醒”的力量。每次有提醒事项时,iPhone就会振动起来,然后显示一个弹出窗口,你可以暂停它,或者把它标记为已完成。另外你还可以设置重复提醒,用来提醒你邮寄每个季度的税单、更新订阅、领薪水等容易忘记的事再好不过了。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 深化市场化改革释放经济增长潜力
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

在主张对华强硬的史蒂夫?班农(Steve Bannon)出局之后,人们就忍不住想要宣布特朗普政府的经济民族主义已死。但这忽视了唐纳德?特朗普(Donald Trump)是怎样一个人——他是一个本能的保护主义者。正如我们近来所了解到的,对于中国,他更想要的是“关税”而不是交易。他还认为打击中国是向其基础选民履行他的“美国优先”承诺的关键。
[in'geid?d]
The 8,000 volunteers who will welcome international visitors to London 2012 have been issued with a 66-page instruction manual, covering everything from foreign etiquette to uniform care and advice on dealing with journalists. But what of the visitors themselves? Could they not do with a manual outlining the customs, manners and practicalities of the islands they are visiting? We hereby present a simple guide to UK etiquette for the 2012 Olympics.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

反对:尽管该片被洛杉矶影评人协会评为最佳剪辑奖,但却没有受到纽约影评人的重视。它的势头会逐渐减弱吗?
[di'klain]
syndrome
Torn Ballet Shoes, and a Life Upended

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

推进农业结构调整。
在《渴望生活》这张专辑的第一首歌《爱》中,拉娜·德雷唱着“过去的一切造就了今天的你,但未来由你决定”。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 今年前三季度建材工业增幅收窄
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

transport
He added that “almost every major Korean company, including Hyundai Motor and AmorePacific, relies heavily on Chinese sales”.
时间:2010-02-24 编辑:vicki

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 前2月一线土地出让增84%
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About this collection

全面提升质量水平。
On Aug 21, the country came to a pause as millions of Americans — even the president — put on eclipse glasses and stopped to take in the first eclipse to cross the United States since 1918. Its path across the United States was a scientific bonanza for astronomers who were able to more easily point advanced equipment at the sun.

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